Han's Medicinal Chemistry & Pharmaceutical Chemistry Lab
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    #76. An Efficient One-Pot Synthesis of Pyrido[2,3-c]coumarins via Serial Catalysis and Its Application in Concise Formal Synthesis of Santiagonamine
    2023.10.18 · The Journal of Organic Chemistry · 88(21):15473-15477
    (DOI) 10.1021/acs.joc.3c01654
    #75. Synthesis of the proposed structure of enhypyrazinone A, a rare marinederived 3,5,6-tri-substituted pyrazinone secondary metabolite
    2023.06.23 · Tetrahedron Letters · 123:154549
    (DOI) 10.1016/j.tetlet.2023.154549
    #74. Exploration of lipidic prodrug-loaded oil depot system for intramuscular prolonged delivery of entecavir
    2023.03.21 · Bulletin of the Korean Chemical Society · 44(7):605-612
    (DOI) 10.1002/bkcs.12699
    #73. Exploration of lipidic prodrug-loaded oil depot system for intramuscular prolonged delivery of entecavir
    2023.03.21 · Bulletin of the Korean Chemical Society · 44(7):605-612
    (DOI) 10.1002/bkcs.12699
    #72. Oleracone F Alleviates Cognitive Impairment and Neuropathology in APPswe PSEN1dE9 Mice by Reducing the Expression of Vascular Cell Adhesion Molecule and Leukocyte Adhesion to Brain Vascular Endothelial Cells
    2023.01.20 · INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES · 24(3):2056
    10.3390/ijms24032056
    #71. Synthesis of a natural quinoline alkaloid isolated from the deep-sea-derived fungus and its potential as a therapeutic for Parkinson's disease
    2022.08.18 · Journal of Asian Natural Products Research · 25(5):446-455
    (DOI) 10.1080/10286020.2022.2104259
    #70. Development and validation of an analytical method to quantify baphicacanthin A by LC-MS/MS and its application to pharmacokinetic studies in mice
    2022.04.25 · 분석과학 · 35(2):60-68
    (기타) 1225-0163(pISSN)
    #69. Synthesis of Evodileptin B, a Natural Anthranilate Derivative Isolated from Evodia lepta, and Evaluation of Its Therapeutic Potential against Parkinson's Disease
    2022.03.20 · Chemistry & Biodiversity · 19(5):e202100808
    (DOI) 10.1002/cbdv.202100808
    #68. RKIP Induction Promotes Tumor Differentiation via SOX2 Degradation in NF2-Deficient Conditions
    2022.03 · MOLECULAR CANCER RESEARCH · 20(3):412-424
    (DOI) 10.1158/1541-7786.MCR-21-0373
    #67. Effect of particle size on in vivo performances of long-acting injectable drug suspension
    2022.01 · Journal of Controlled Release · 341:533-547
    (DOI) 10.1016/j.jconrel.2021.12.011
    #66. Synthesis and Structural Confirmation of the Thiazole Alkaloids Derived from Peganum harmala L
    2021.12.22 · Applied Sciences · 12(1):78
    (DOI) 10.3390/app12010078
    #65. Development of a Sensitive Analytical Method of Polynemoraline C Using LC-MS/MS and Its Application to a Pharmacokinetic Study in Mice
    2021.12 · Mass Spectrometry Letters · 12(4):200-205
    10.5478/MSL.2021.12.4.200
    SCOPUS
    #64. Synthesis of Proposed Structure of Aaptoline A, a Marine Sponge-Derived 7,8-Dihydroxyquinoline, and Its Neuroprotective Properties in C. elegans
    2021.10.01 · Molecules · 26(19):5964
    (DOI) 10.3390/molecules26195964
    #63. Synthesis of Proposed Structure of Aaptoline B via Transition Metal-Catalyzed Cycloisomerization and Evaluation of Its Neuroprotective Properties in C. Elegans
    2021.09.30 · Applied Sciences · 11(19):9125
    (DOI) 10.3390/app11199125
    #62. Synthesis of the proposed structure of sibiriaester B and evaluation of its immunomodulatory properties
    2021.09.14 · Bulletin of the Korean Chemical Society · 42(11):1430-1434
    (DOI) 10.1002/bkcs.12392
    #61. Antitumor Activity of Novel Signal Transducer and Activator of Transcription 3 Inhibitors on Retinoblastoma
    2021.07 · Molecular Pharmacology · 100(1):63-72
    (DOI) 10.1124/molpharm.120.000231
    #60. Liquid chromatography-tandem mass spectrometric analysis of oleracone d and its application to pharmacokinetic study in mice
    2021.06 · 분석과학 · 34(5):193-201
    (DOI) 10.5806/AST.2021.34.5.193
    KCI
    #59. Liquid chromatography-tandem mass spectrometric analysis of nannozinone a and its application to pharmacokinetic study in mice
    2021.03.21 · Mass Spectrometry Letters · 12(1):21-25
    (DOI) 0.5478/MSL.2021.12.1.000
    SCOPUS
    #58. Neuroprotective effect of damaurone D in a C. elegans model of Parkinson's disease
    2021.03.16 · Neuroscience Letters · 747(16):135623
    (DOI) 10.1016/j.neulet.2021.135623
    SCI(E)
    #57. 엘레간스 리아트리스 유래 새로운 페놀성 화합물인 파라-히드록시페닐퍼룰레이트의 제안구조 합성 연구
    2020.12 · 약학회지 · 64(6):461-464
    0377-9556(pISSN)
    KCI
    #56. Longevity effects of hispidol in Caenorhabditis elegans
    2020.11.12 · BioFactors · 46(6):1041-1048
    (DOI) 10.1002/biof.1695
    #55. Preliminary Study on Novel Expedient Synthesis of 5-Azaisocoumarins by Transition Metal-Catalyzed Cycloisomerization
    2020.09.04 · Frontiers in Chemistry · 8:772
    (DOI) 10.3389/fchem.2020.00772
    #54. A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction
    2020.08 · Biochemical Pharmacology · 178:114053
    (DOI) 10.1016/j.bcp.2020.114053
    #53. The first synthesis and immunomodulatory properties of p-hydroxyphenyl caffeate derived from Wedelia trilobata
    2019.11.18 · Journal of Asian Natural Products Research · 22(10):966-975
    (DOI) 10.1080/10286020.2019.1680643
    #52. Development of sensitive analytical method of rhodanthpyrone a by a lc-ms/ms and its application to bioavailability study in rats
    2019.09.30 · Mass Spectrometry Letters · 10(3):88-92
    (DOI) 10.5478/MSL.2019.10.3.88
    #51. Efficient Synthesis of Pyrido[3,2-c]coumarins via Silver Nitrate Catalyzed Cycloisomerization and Application to the First Synthesis of Polyneomarline C
    2019.09.30 · Synthesis · 51(24):4611-4618
    (DOI) 10.1055/s-0037-1610730
    SCI(E)
    #50. Synthesis and Evaluation of the Lifespan-Extension Properties of Oleracones D–F, Antioxidative Flavonoids from Portulaca oleracea L.
    2019.09.25 · Applied Sciences · 9(19):4014
    (DOI) 10.3390/app9194014
    #49. Rhodanthpyrone A and B play an anti-inflammatory role by suppressing the nuclear factor-kappa B pathway in macrophages
    2019.09 · The Korean Journal of Physiology & Pharmacology · 23(6):493-499
    (DOI) 10.4196/kjpp.2019.23.6.493
    #48. The First Synthesis of Baphicacanthin A, a Natural Phenoxazinone Alkaloid Derived from Baphicacanthus cusia
    2019.06.17 · Bulletin of the Korean Chemical Society · 40(7):740-742
    (DOI) 10.1002/bkcs.11756
    SCI(E)
    #47. Concise Synthesis of Nannozinone A: An Unusual Dihydropyrrolopyrazinone Metabolite From Myxobacteria
    2019.06.17 · Natural Product Communications · 14(6)
    (DOI) doi.org/10.1177/1934578X19857493
    #46. Novel Galiellalactone Analogues Can Target STAT3 Phosphorylation and Cause Apoptosis in Triple-Negative Breast Cancer
    2019.05.03 · Biomolecules · 9(5):170
    (DOI) 10.3390/biom9050170
    #45. Development and validation of an LC-MS/MS method for determination of damaurone d in rat plasma and its application to pharmacokinetic study in rats
    2019.03.31 · Mass Spectrometry Letters · 10(1):38-42
    (DOI) 10.5478/MSL.2019.10.1.38
    SCOPUS
    #44. Discovery and SAR studies of novel 2-anilinopyrimidine-based selective inhibitors against triple-negative breast cancer cell line MDA-MB-468
    2019.01.01 · Bioorganic & Medicinal Chemistry Letters · 29(1):62-65
    (DOI) 10.1016/j.bmcl.2018.11.010
    #43. Recent Advances in Synthesis of 4-Arylcoumarins
    2018.09.20 · Molecules · 23(10):2417
    (DOI) 10.3390/molecules23102417
    #42. Total Synthesis of the Natural Pyridocoumarins Goniothaline A and B
    2018.09.17 · Synthesis · 51(2):552-556
    (DOI) 10.1055/s-0037-1610909
    SCI(E)
    #41. Design and in vivo evaluation of entecavir-3-palmitate microcrystals for subcutaneous sustained delivery
    2018.09 · European Journal of Pharmaceutics and Biopharmaceutics · 130:143-151
    10.1016/j.ejpb.2018.06.024
    #40. Antiageing properties of Damaurone D in Caenorhabditis elegans
    2018.07.10 · Journal of Pharmacy and Pharmacology · 70(10):1423-1429
    (DOI) 10.1111/jphp.12979
    #39. Microsuspension of fatty acid esters of entecavir for parenteral sustained delivery
    2018.05.30 · International Journal of Pharmaceutics · 543(1-2):52-59
    (DOI) 10.1016/j.ijpharm.2018.03.042
    #38. Synthesis and Physicochemical Evaluation of Entecavir-Fatty Acid Conjugates in Reducing Food Effect on Intestinal Absorption
    2018.03.22 · Molecules · 234(4):731
    (DOI) 10.3390/molecules23040731
    #37. Synthesis of Ficusnotins, Rare 1,4-Diarylbutanoids Derived from Ficusnota, via Ruthenium-Catalyzed Conjugate Addition
    2018.03.01 · Natural Product Communications · 13(3):351-353
    (DOI) 10.1177/1934578X1801300320
    SCI(E)
    #36. An Improved C-Deglycosylation of Mangiferin to Norathyriol
    2018.02.08 · Organic Preparations and Procedures International · 50(1):91-94
    (DOI) doi.org/10.1080/00304948.2017.1405336
    #35. Dihydropyranoaurone compound damaurone D inhibits LPS-induced inflammation and liver injury by inhibiting NF-kappa B and MAPK signaling independent of AMPK
    2017.12.23 · Archives of Pharmacal Research · 41(3):314-323
    (DOI) 10.1007/s12272-017-1001-3
    #34. Concise synthesis of the bioactive natural polyhydroxynaphthoate parvinaphthol B via Hauser-Kraus annulation
    2017.12.20 · Tetrahedron Letters · 58(51):4779-4780
    (DOI) 10.1016/j.tetlet.2017.11.024
    #33. Identification of aminosulfonylarylisoxazole as microRNA-31 regulators
    2017.08.04 · PLOS ONE · 12(8):e0182331
    (DOI) 10.1371/journal.pone.0182331
    #32. Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis
    2017.06.26 · Molecules · 22(7):1069
    (DOI) 10.3390/molecules22071069
    #31. Concise and Efficient Synthesis of 3,7-Dioxo-5-cholanic Acid via C3,C7-Selective Ketal Protection
    2017.04.20 · Organic Preparations and Procedures International · 49(2):163-168
    (DOI) 10.1080/00304948.2017.1291005
    #30. Synthesis and anti-inflammatory activities of novel dihydropyranoaurone derivatives
    2017.04.10 · Archives of Pharmacal Research · 40(6):695-703
    (DOI) 10.1007/s12272-017-0910-5
    #29. Synthesis of proposed structure of rennellianone B: A study on rearrangement of anthraquinonyl propargyl ether toward 2H-pyranoanthraquinone
    2017.02.08 · Tetrahedron Letters · 58(6):556-558
    (DOI) 10.1016/j.tetlet.2016.12.080
    #28. Recent advanced in the synthesis of biologically active cinnoline, phthalazine and quinoxaline derivatives
    2017.02 · Current Organic Chemistry · 21(14):1265-1291
    10.2174/1385272821666170221150901
    SCI(E)
    #27. A Concise Synthesis of Rhodanthpyrone A and B, Natural 4-(Hydroxyphenyl)-substituted α-Pyrones
    2017.01 · Natural Product Communications · 12(1):95-98
    (DOI) 10.1177/1934578X1701200127
    SCI(E)
    #26. 산자나무열매 유래 천연 히드록시신남아마이드의 실용적 합성
    2016.09 · 약학회지 · 60(5):261-264
    (기타) 0377-9556(pISSN)
    KCI
    #25. Metrodorea stipularis 유래 생리활성 크로마노-디히드로칼콘의 합성
    2016.07.25 · 약학회지 · 60(4):207-210
    (기타) 0377-9556(pISSN)
    KCI
    #24. Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool -Amino Acids for Natural Product Synthesis
    2016.07.21 · Molecules · 21(7):951
    (DOI) 10.3390/molecules21070951
    #23. 예쁜꼬마선충을 이용한 레오누린과 그 합성 분절 유도체의수명연장 효과 연구
    2016.06.30 · 약학회지 · 60(3):141-145
    (기타) 0377-9556(pISSN)
    #22. A practical and eco-friendly synthesis of oxo-bile acids
    2016.01.29 · Organic Preparations and Procedures International · 48(1):55-61
    10.1080/00304948.2016.1127101
    #21. Identification of small molecule inhibitors of the STAT3 signaling pathway: insights into their structural features and mode of action
    2015.11.15 · Bioorganic & Medicinal Chemistry Letters · 25(22):5444-5448
    (DOI) 10.1016/j.bmcl.2015.07.063
    #20. Diastereoselective Total Synthesis of (-)-Galiellalactone
    2015.11.06 · The Journal of Organic Chemistry · 80(24):12193-12200
    (DOI) 10.1021/acs.joc.5b02121
    #19. Synthesis of the proposed structure of damauone D and evaluation of its anti-inflammatory activity
    2015.08.20 · Chemical & Pharmaceutical Bulletin · 63(11):907-912
    (DOI) 10.1248/cpb.c15-00528
    #18. Studies on the synthesis of indothiazinone and its derivatives via direct 3-acylation of indole
    2015.05.15 · Synthetic Communications · 45(14):1662-1668
    doi.org/10.1080/00397911.2015.1040513
    #17. 팔라듐 촉매하 결합반응을 이용한 플루비프로펜의 간결한 합성
    2015.04.30 · 약학회지 · 59(2):66-69
    0377-9556(pISSN)
    #16. Design, synthesis, and biological evaluation of pyrimidine-2-carboxamide analogs: investigation for novel RAGE inhibitors with reduced hydrophobicity and toxicity
    2015.04.05 · Archives of Pharmacal Research · 38(11):1952-1962
    (DOI) 10.1007/s12272-015-0596-5
    #15. Fine tuning of 4,6-bisphenyl-2-(3-alkoxyanilino)pyrimidine focusing on the activity-sensitive aminoalkoxy moiety for a therapeutically useful inhibitor of receptor for advanced glycation end products (RAGE)
    2015.02.01 · Bioorganic & Medicinal Chemistry · 23(3):579-587
    (DOI) 10.1016/j.bmc.2014.12.003
    #14. Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE)
    2014.05.22 · European Journal of Medicinal Chemistry · 79:128-142
    (DOI) 10.1016/j.ejmech.2014.03.072
    #13. A novel cantharidin analog N-Benzylcantharidinamide reduces the expression of MMP-9 and invasive potentials of Hep3B via inhibiting cytosolic translocation of HuR
    2014.05.02 · Biochemical and Biophysical Research Communications · 447(2):371-377
    (DOI) 10.1016/j.bbrc.2014.04.035
    #12. Glucal-conjugated sterols as novel vascular leakage blocker: Structure-activity relationship focusing on the C-17-side chain
    2014.03.21 · European Journal of Medicinal Chemistry · 75:184-194
    (DOI) 10.1016/j.ejmech.2014.01.027
    #11. 복합한약제제가 Pentobarbital에 의해 유도된 수면시간에 미치는 영향
    2013.12.25 · 동의생리병리학회지 · 27(6):759-763
    1738-7698(pISSN)
    #10. 디아조크로마논과 보론산의 팔라듐 촉매하 결합반응을 이용한Lespedezol A1의 합성
    2013.10.31 · 약학회지 · 57(5):357-361
    0377-9556(pISSN)
    #9. Stereoselective Synthesis of 7-epi-Incarvilline
    2013.01.23 · Organic Letters · 15(3):531-533
    10.1021/ol303395f
    #8. Heterocycle-linked Phenylbenzyl Amides as Novel TRPV1 Antagonists and Their TRPV1 Binding Modes: Constraint-Induced Enhancement of In Vitro and In Vivo Activities
    2012.12.03 · Chemistry – An Asian Journal · 8(2):400-409
    10.1002/asia.201200730
    #7. Design, Synthesis, and Biological Evaluation of Novel Deguelin-Based Heat Shock Protein 90 (HSP90) Inhibitors Targeting Proliferation and Angiogenesis
    2012.11.27 · Journal of Medicinal Chemistry · 55(24):10863-10884
    10.1021/jm301488q
    #6. Ligand-Based Design, Synthesis, and Biological Evaluation of 2-Aminopyrimidines, a Novel Series of Receptor for Advanced Glycation End Products (RAGE) Inhibitors
    2012.06.28 · Journal of Medicinal Chemistry · 55(21):9120-9135
    10.1021/jm300172z
    #5. Asymmetric Syntheses of 1-Deoxy-6,8a-di-epi-castanospermine and 1-Deoxy-6-epi-castanospermine
    2012.05.21 · The Journal of Organic Chemistry · 77(12):5389-5393
    10.1021/jo300309z
    #4. Novel Human Umbilical Vein Endothelial Cells (HUVEC)-Apoptosis Inhibitory Phytosterol Analogues: Insight into Their Structure-Activity Relationships
    2012.04.05 · Archives of Pharmacal Research · 35(3):455-460
    10.1007/s12272-012-0308-3
    SCI(E)
    #3. A Versatile Synthetic Approach to Grandisol Monoterpene Pheromone
    2011.10.06 · Archives of Pharmacal Research · 34(9):1437-1442
    10.1007/s12272-011-0904-7
    SCI(E)
    #2. Thermodynamic equilibration in Pd(0)-catalyzed interconversion of highly constrained [2.1.2] bicyclic lactones: its mechanistic investigation
    2010.05.19 · Tetrahedron Letters · 51(20):2697-2699
    https://doi.org/10.1016/j.tetlet.2010.03.016
    #1. Discovery of Highly Potent Multidrug Resistance (MDR) Reversal Agents: Aminosulfonylaryl Isoxazole Derivatives
    2009.04.20 · Bulletin of the Korean Chemical Society · 30(4):779-780
    10.5012/bkcs.2009.30.4.779
    SCI(E)