Development of Osteoporotic Fracture Risk Assessment by Machine Learning
The aim of this research project is the development of supervised machine learning models for the prediction of geometrical and environmental conditions leading to bone fragility.
By working together with a partner hospital, the aim is to develop useful tools for fracture prediction while enhancing the understanding of the complex phenomenon represented by bone fracture.
The current state of the research is based on three high-level supervised machine learning models (Extreme Gradient Boosting, K-Nearest Neighbor, and Deep Neural Network) and already showed high fracture risk prediction accuracy (~95%).
Further development shall aim at develop location-specific (i.e. lower limbs, upper limbs, spine, etc.) fracture risk assessment models to be further combined into an overall risk factor for the patient. In addition, complementary aspects such as synthetic data generation, machine learning model structure, and pre-processing are aimed to be considered as well during the research.